Tuberculosis Immune Drug

Jakarta, Kompas - the more severe tuberculosis prevention expense with the emergence of drug resistant cases of tuberculosis (TB-resistant multidrugs). The biggest immune cause of tuberculosis germs to anti tuberculosis drugs because the man-made factors.
Pulmonary specialists at the same time President General Hospital Center (Dr) Friendship, Priyanti Z Soepandi, said that the talk show themed "Prevent TB Drug Invulnerability", held Dr Friendship, Tuesday (20 / 4).
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. The disease is transmitted by air through a spray of sputum of TB patients. Most of these bacteria attack the lungs, but can also be related to other organs.
In the world, most tuberculosis sufferers in India, China and Indonesia. In Indonesia, there are about 500,000 new cases of TB per year.
Priyanti said, TB is drug resistant TB is caused by TB germs are resistant to at least two anti-TB drugs, namely isonicotinylhydrazine (INH) and rifampicin together or with resistance to other first-line TB drugs, such as Ethambutol, streptomycin, and pirazinamide. Isoniazid and rifampicin are the backbone of TB treatment.
Based on the report of World Health Organization (WHO) and the Ministry of Health which is spread on Tuberculosis Day, March 24, the estimated incidence of 2-3 per cent of drug resistant TB among new cases. Estimated number of drug resistant TB patients among the overall cases of TB in Indonesia in the year 2007 about 12,209 inhabitants. Approximate incident-multidrugs resistant tuberculosis (MDR-TB) reached 6395 cases per year. Until mid-March
2010 found 69 patients with drug resistant TB has been confirmed and partially treated.
Drug resistant TB is also the world's attention. In the year 2008, there are 440,000 reported cases of drug resistant TB which causes 150,000 deaths. Approximately 28 percent of drug resistant TB cases in Southeast Asia.
Human activities
According Priyanti, increased resistance to multiple TB germs to anti-TB drugs caused the greatest human activities alone. Natural resistance or mutation is very small. The cause of the occurrence of drug resistant TB from the health service, among others
improper treatment, improper dosages, drug supply uncertainty, and poor storage of drugs. The resistance to first-line drugs can also be caused by the patients themselves, such as disobedience to consume drugs, not taking the drugs as required, and end treatment.
He said the treatment of drug resistant TB is much more difficult, long, and expensive. Treatment takes at least two years and six months of taking injections in the buttocks left and right. Drug prices are also many times more expensive. Enforcement is also more difficult to diagnose. "Currently, the government was having a trial project management of drug resistant TB in the department of Friendship and dr Soetomo, Surabaya," he said.
Drug resistant TB is different from the usual TB treatment should only take six months and the price of cheaper drugs. TB drugs are available in government health services for free.
If not treated properly, patients can get into the condition of extensively drug resistant tuberculosis, or XDR, ie MDR-TB with resistance to second-line TB drugs, namely fluoroquinolon groups and at least one anti-TB second-line injections, such as kanamycin, amikacin, and capreomycin.
Another speaker, clinical pathology specialists, Endang Woro, say, the control and prevention of TB infection can be done by implementing clean and healthy lifestyle behaviors. Behaviors include getting used to wash hands before and after working on something. Other prevention by closing the mouth during coughing, phlegm not carelessly discard, and ventilation is good. (Ine)